Constance L. Saw: search on Z-Library

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1

Astaxanthin and omega-3 fatty acids individually and in combination protect against oxidative stress via the Nrf2–ARE pathway

Saw, Constance Lay Lay, Yang, Anne Yuqing, Guo, Yue, Kong, Ah-Ng Tony

Journal:

Food and Chemical Toxicology

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

2

Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia

Amanda K. Smolarek, Jae Young So, Paul E. Thomas, Hong Jin Lee, Shiby Paul, Anne Dombrowski, Chung-Xiou Wang, Constance Lay-Lay Saw, Tin Oo Khor, Ah-Ng Tony Kong, Kenneth Reuhl, Mao-Jung Lee, Chung S.

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

3

Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates

Constance Lay-Lay Saw, Melvilí Cintrón, Tien-Yuan Wu, Yue Guo, Ying Huang, Woo-Sik Jeong, Ah-Ng Tony Kong

Journal:

Biopharmaceutics & Drug Disposition

Year:

2011

Language:

english

File:

PDF, 358 KB

english, 2011

4

Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane

Constance L. Saw, Mou-Tuan Huang, Yue Liu, Tin Oo Khor, Allan H. Conney, Ah-Ng Kong

Journal:

Molecular Carcinogenesis

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

5

Induction of NRF2-mediated gene expression by dietary phytochemical flavones apigenin and luteolin

Paredes-Gonzalez, Ximena, Fuentes, Francisco, Jeffery, Sundrina, Saw, Constance Lay-Lay, Shu, Limin, Su, Zheng-Yuan, Kong, Ah-Ng Tony

Journal:

Biopharmaceutics & Drug Disposition

Year:

2015

Language:

english

File:

PDF, 470 KB

english, 2015

6

Use of fish-oil: Docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) for chronic psychological stress

Saw, Constance Lay Lay

Journal:

Advances in Integrative Medicine

Year:

2018

Language:

english

File:

PDF, 195 KB

english, 2018

7

Effects of natural phytochemicals in Angelica sinensis (Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation

Saw, Constance Lay Lay, Wu, Qing, Su, Zheng-Yuan, Wang, Hu, Yang, Yinhua, Xu, Xiaoting, Huang, Ying, Khor, Tin Oo, Kong, Ah-Ng Tony

Journal:

Biopharmaceutics & Drug Disposition

Year:

2013

Language:

english

File:

PDF, 219 KB

english, 2013

8

Spectroscopic characterization and photobleaching kinetics of hypericin-N-methyl pyrrolidone formulations

Saw, Constance Lay Lay, Olivo, Malini, Soo, Khee Chee, Heng, Paul Wan Sia

Journal:

Photochemical & Photobiological Sciences

Year:

2006

Language:

english

File:

PDF, 285 KB

english, 2006

9

Enhanced photodynamic activity of hypericin by penetration enhancer N-methyl pyrrolidone formulations in the chick chorioallantoic membrane model

Constance Lay Lay Saw, Paul Wan Sia Heng, William Wei Lim Chin, Khee Chee Soo, Malini Olivo

Journal:

Year:

2006

Language:

english

File:

PDF, 175 KB

english, 2006

10

Epigenetic Modifications of Nrf2 by 3,3′-diindolylmethaneIn Vitroin TRAMP C1 Cell Line andIn VivoTRAMP Prostate Tumors

Wu, Tien-Yuan, Khor, Tin Oo, Su, Zheng-Yuan, Saw, Constance Lay-Lay, Shu, Limin, Cheung, Ka-Lung, Huang, Ying, Yu, Siwang, Kong, Ah-Ng Tony

Journal:

The AAPS Journal

Year:

2013

Language:

english

File:

PDF, 626 KB

english, 2013

11

Study of interaction of hypericin and its pharmaceutical preparation by fluorescence techniques

Olivo, Malini, Sudhaharan, Thankiah, Ahmed, Sohail, Heng, Paul Wan Sia, Wohland, Thorsten, Liu, Jun, Saw, Constance Lay Lay

Journal:

Journal of Biomedical Optics

Year:

2009

Language:

english

File:

PDF, 260 KB

english, 2009

12

Metabolism, oral bioavailability and pharmacokinetics of chemopreventive kaempferol in rats

Avantika Barve, Chi Chen, Vidya Hebbar, Joseph Desiderio, Constance Lay-Lay Saw, Ah-Ng Kong

Journal:

Biopharmaceutics & Drug Disposition

Year:

2009

Language:

english

File:

PDF, 155 KB

english, 2009

13

Altered behavioral development in Nrf2 knockout mice following early postnatal exposure to valproic acid

Furnari, Melody A., Saw, Constance Lay-Lay, Kong, Ah-Ng, Wagner, George C.

Journal:

Brain Research Bulletin

Year:

2014

Language:

english

File:

PDF, 883 KB

english, 2014

14

Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells

Limin Shu, Tin Oo Khor, Jong-Hun Lee, Sarandeep S. S. Boyanapalli, Ying Huang, Tien-Yuan Wu, Constance L.-L. Saw, Ka-Lung Cheung, Ah-Ng Tony Kong

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

15

Anti-NF-κB and anti-inflammatory activities of synthetic isothiocyanates: Effect of chemical structures and cellular signaling

Auemduan Prawan, Constance Lay Lay Saw, Tin Oo Khor, Young-Sam Keum, Siwang Yu, Longqin Hu, Ah-Ng Kong

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

16

Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin

Boyanapalli, Sarandeep S. S., Paredes-Gonzalez, Ximena, Fuentes, Francisco, Zhang, Chengyue, Guo, Yue, Pung, Doug, Saw, Constance Lay Lay, Kong, Ah-Ng Tony

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

17

The Study of Interaction of Hypericin And Its Pharmaceutical Preparation by Fluorescence Techniques

Liu, Jun, Saw, Constance Lay Lay, Olivo, Malini, Sudhaharan, Thankiah, Ahmed, Sohail, Heng, Paul Wan Sia, Wohland, Thorsten

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

18

Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress/anti-inflammatory pathways

Constance Lay-Lay Saw, Qing Wu, Ah-NgTony Kong

Journal:

Chinese Medicine

Year:

2010

Language:

english

File:

PDF, 707 KB

english, 2010

19

Regulation of NF-E2-Related Factor 2 Signaling for Cancer Chemoprevention: Antioxidant Coupled with Antiinflammatory

Hu, Rong, Saw, Constance Lay-Lay, Yu, Rong, Kong, Ah-Ng Tony

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

20

Pharmacokinetics and Pharmacodynamics of Phase II Drug Metabolizing/Antioxidant Enzymes Gene Response by Anticancer Agent Sulforaphane in Rat Lymphocytes

Wang, Hu, Khor, Tin Oo, Yang, Qian, Huang, Ying, Wu, Tien-yuan, Saw, Constance Lay-Lay, Lin, Wen, Androulakis, Ioannis P., Kong, Ah-Ng Tony

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 336 KB

english, 2012

21

Chick Chorioallantoic Membrane as an In Situ Biological Membrane for Pharmaceutical Formulation Development: A Review

Saw, Constance L. L., Heng, Paul W. S., Liew, Celine V.

Journal:

Drug Development and Industrial Pharmacy

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

22

Antimicrobial and antioxidant activities ofCortex Magnoliae Officinalisand some other medicinal plants commonly used in South-East Asia

Lai Wah Chan, Emily LC Cheah, Constance LL Saw, Wanyu Weng, Paul WS Heng

Journal:

Chinese Medicine

Year:

2008

Language:

english

File:

PDF, 877 KB

english, 2008

23

Oxidative Stress and Bladder Cancer Carcinogenesis: Early Detection and Chemoprevention Involving Nrf2—an Integrative Approach

Saw, Constance Lay Lay

Journal:

Current Pharmacology Reports

Year:

2018

Language:

english

File:

PDF, 918 KB

english, 2018

24

Pharmacodynamics of Ginsenosides: Antioxidant Activities, Activation of Nrf2, and Potential Synergistic Effects of Combinations

Saw, Constance Lay Lay, Yang, Anne Yuqing, Cheng, David C., Boyanapalli, Sarandeep S.-S., Su, Zheng-Yuan, Khor, Tin Oo, Gao, Song, Wang, Jingrong, Jiang, Zhi-Hong, Kong, Ah-Ng Tony

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.04 MB

english, 2012

25

Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer

Saw, Constance Lay Lay, Kong, Ah-Ng Tony

Journal:

Expert Opinion on Therapeutic Targets

Year:

2011

Language:

english

File:

PDF, 553 KB

english, 2011

26

In vivo pharmacodynamics of indole-3-carbinol in the inhibition of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Involvement of Nrf2 and cell cycle/apoptosis signaling pathways

Tien-Yuan Wu, Constance Lay-Lay Saw, Tin Oo Khor, Douglas Pung, Sarandeep S.S. Boyanapalli, Ah-Ng Tong Kong

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 218 KB

english, 2012

27

Epigenetic Reactivation of Nrf2 in Murine Prostate Cancer TRAMP C1 Cells by Natural Phytochemicals Z-Ligustilide and Radix Angelica Sinensis via Promoter CpG Demethylation

Su, Zheng-Yuan, Khor, Tin Oo, Shu, Limin, Lee, Jong Hun, Saw, Constance Lay-Lay, Wu, Tien-Yuan, Huang, Ying, Suh, Nanjoo, Yang, Chung S., Conney, Allan H., Wu, Qing, Kong, Ah-Ng Tony

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 3.00 MB

english, 2013

28

Anti-inflammatory/Anti-oxidative Stress Activities and Differential Regulation of Nrf2-Mediated Genes by Non-Polar Fractions of TeaChrysanthemum zawadskiiand LicoriceGlycyrrhiza uralensis

Tien-Yuan Wu, Tin Oo Khor, Constance Lay Lay Saw, Stephanie C. Loh, Alvin I. Chen, Soon Sung Lim, Jung Han Yoon Park, Li Cai, Ah-Ng Tony Kong

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 657 KB

english, 2011

29

Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages

Saw, Constance Lay, Yang, Anne, Huang, Mou-Tuan, Liu, Yue, Lee, Jong, Khor, Tin, Su, Zheng-Yuan, Shu, Limin, Lu, Yaoping, Conney, Allan H, Kong, Ah-Ng

Journal:

Cell & Bioscience

Year:

2014

Language:

english

File:

PDF, 844 KB

english, 2014

30

Role of Nrf2 in Suppressing LPS-Induced Inflammation in Mouse Peritoneal Macrophages by Polyunsaturated Fatty Acids Docosahexaenoic Acid and Eicosapentaenoic Acid

Wang, Hu, Khor, Tin Oo, Saw, Constance Lay Lay, Lin, Wen, Wu, Tienyuan, Huang, Ying, Kong, Ah-Ng Tony

Journal:

Molecular Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

31

Transport of Hypericin across Chick Chorioallantoic Membrane and Photodynamic Therapy Vasculature Assessment

Saw, Constance Lay Lay, Olivo, Malini, Chin, William Wei Lim, Soo, Khee Chee, Heng, Paul Wan Sia

Journal:

Biological & Pharmaceutical Bulletin

Year:

2005

Language:

english

File:

PDF, 499 KB

english, 2005

32

Synergistic anti-inflammatory effects of low doses of curcumin in combination with polyunsaturated fatty acids: Docosahexaenoic acid or eicosapentaenoic acid

Constance Lay Lay Saw, Ying Huang, Ah-Ng Kong

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 661 KB

english, 2010

33

The berry constituents quercetin, kaempferol, and pterostilbene synergistically attenuate reactive oxygen species: Involvement of the Nrf2-ARE signaling pathway

Saw, Constance Lay Lay, Guo, Yue, Yang, Anne Yuqing, Paredes-Gonzalez, Ximena, Ramirez, Christina, Pung, Douglas, Kong, Ah-Ng Tony

Journal:

Food and Chemical Toxicology

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

34

Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model

Constance Lay Lay Saw, Malini Olivo, William Wei Lim Chin, Khee Chee Soo, Paul Wan Sia Heng

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2007

Language:

english

File:

PDF, 802 KB

english, 2007

35

Delivery of hypericin for photodynamic applications

Constance Lay Lay Saw, Malini Olivo, Khee Chee Soo, Paul Wan Sia Heng

Journal:

Year:

2006

Language:

english

File:

PDF, 128 KB

english, 2006

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